MolYsis-SNplus™ IVD (not available in USA)
MolYsis-SNplus™ IVD is a kit for automated human DNA depletion and bacterial & fungal DNA isolation from diverse human specimens.
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The presence of large amounts of human DNA can introduce "background noise" when using molecular techniques such as PCR or Next Generation Sequencing (NGS).
The combination of human DNA depletion with contamination-free reagents and plastics maximizes the chances of detecting microbial DNA directly from human samples even at low levels, ensuring that even trace amounts can be captured and analysed.
The MolYsis-SNplus™ IVD kit has been developed with the objective of providing laboratory professionals with a tool that facilitates the automated extraction of bacterial and fungal DNA from human samples, while simultaneously depleting the human DNA background. The method has been validated for a wide range of samples, including body fluids, swabs, and tissues.
MolYsis-SNplus™ IVD complies with the following European regulations: Regulation (EU) 2017/746 on In Vitro Diagnostic Medical Devices (IVDR).
Internal Extraction Control
An optional internal extraction control testing can be performed with each sample in order to validate the extraction of DNA.
The Buffer Cartridges included in the MolYsis-SNplus™ IVD kit contain an internal extraction control DNA which is passed through the extraction process ending up in the eluate. The internal extraction control is a DNA template used as a process control to validate the DNA extraction.
To perform the extraction control, the separately available Control PCR kit must be used.
Please note: The Control PCR assay is not included in the MolYsis-SNplus™ IVD kit and needs to be ordered separately!
Order information:
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Application
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Content
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Order No.
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Quotation Request
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MolYsis-SNplus™ IVD |
Kit for automated human DNA depletion and bacterial & fungal DNA isolation from human samples. | 48 reactions | U-300-048 | Request form |
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Control PCR (Research Use Only) |
Internal extraction control assay to be used with MolYsis-SNplus™ IVD | 48 reactions | S-080-0048 | |
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SelectNA™plus robot |
Instrument for fully automated microbial DNA extraction | 1 instrument | D-400-001 |
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Product Flyer
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Other
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November 2024
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| Manuals and Datasheet Version numbers | November 2024 |
Please inquire for more detailed information at Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein! or call at +49 (0) 421 / 69 61 62 0.
Selected references:
Kantor J, Abendroth B, Mühl H, Drevinek P (2024) Evaluation and optimization of a host DNA depletion workflow in complex clinical samples for the direct detection of pathogens by NGS shotgun sequencing; Poster Presentation on 13th European Meeting on Molecular Diagnostics (EMMD)