Stay informed on topics covering pathogen enrichment and DNA isolation from clinical samples, automation, molecular diagnostics and Next-Generation Sequencing. We keep you informed on new developments, give practical tips and provide an inside view on Molzym.
|Pathogen DNA Isolation||NGS||Automation|
|DNA-Free Reagents||Molecular Diagnostics||Newsletter|
Rapid pathogen detection is essential for timely patient treatment. In contrast to culture, molecular methods provide results within hours. Molzym’s highly sensitive approach combines a unique DNA extraction technique with 16S and 18S rRNA gene PCR and amplicon sequencing for the identification of bacterial and fungal infections. See how it works.
Invasive fungal disease is a major cause of morbidity and mortality in immuno-compromised patients. In a FP7 project of the European Commission, Molzym partners with 5 institutions from 4 countries to develop and evaluate in multi-centre clincial studies fast DNA, enzymatic and protein-based assays.
Remove your host DNA for increased sensitivity for detection of microbes in a great variety of specimens, e.g body fluids and tissues. Here, we provide a collection of applications of MolYsis™ sample pre-treatment in combination with various analytical methods, including NGS, PCR and Real-time PCR, DNA arrays and amplicon cloning.
Micro-Dx™ combines automated pathogen enrichment and DNA extraction with broad-range PCR and sequencing ID of species. A multi-centre analysis of 409 routine samples of tissues, fluids and swabs indicated acceptable diagnostic performance in comparison to other molecular tests and culture. Additional pathogens could be identified by Micro-Dx™.
One of the major challenges in molecular microbe detection are false-positive results due to DNA contaminations of amplification reagents. Molzym’s new proprietary Hot MolTaq 16S/18S is a high quality, DNA-free Taq DNA polymerase ideally suited for the sensitive PCR analysis of microbial target DNA even at very low concentrations. Find out the benefits.