Molzym Blog

Molzym Blog

Stay informed on topics covering pathogen enrichment and DNA isolation from clinical samples, automation, molecular diagnostics and Next Generation Sequencing. We keep you informed on new developments, give practical tips and provide an inside view on Molzym.

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Pathogen DNA Isolation NGS Automation
DNA-Free Reagents Molecular Diagnostics Newsletter
 
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Latest blog posts - Click here for the list of our latest blog posts

 

Selection of blog posts:

Join the Molzym Workshop at REMMDI on 11th of April

At the approaching REMMDI Meeting in Regensburg from 11th to 13th of April 2019, the Molzym experts invite you to our workshop covering in-depth insights of implementation of culture-independent analysis of pathogens by broad-range PCR in clinical routine. Learn about the benefit of Micro-Dx™ and SepsiTest™-UMD in exciting case studies. Safe your seat!

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Standardised Method for Infection Diagnosis with NGS

In a poster presentation at ECCMID 2018 congress, Edelmann et al. [1] compared 4 DNA extraction kits and the influence of human DNA removal for use in microbiome analysis. Additionally, two master mixes were tested for bacterial DNA contamination. An efficient workflow towards a standardised use of NGS in infection diagnosis was proposed.

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SepsiTest™-UMD: Unbiased rDNA PCR Pathogen Diagnosis

Rapid pathogen detection is essential for timely patient treatment. In contrast to culture, molecular methods provide results within hours. Molzym’s highly sensitive approach combines a unique DNA extraction technique with 16S and 18S rRNA gene PCR and amplicon sequencing for the identification of bacterial and fungal infections. See how it works.

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MolYsis™ Host DNA Removal – Effect on Pathogen Analysis

In clinical specimens with low microbial load, host DNA at large excess negatively influences amplification of target pathogen DNA. This contribution guides through Molzym’s MolYsis™ technology of host DNA removal in front of microbial DNA extraction systems. The positive effect of host DNA removal on molecular analysis is discussed.

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DNA-Free Hot MolTaq 16S/18S: Low Load Microbial DNA Detection

One of the major challenges in molecular microbe detection are false-positive results due to DNA contaminations of amplification reagents. Molzym’s new proprietary Hot MolTaq 16S/18S is a high quality, DNA-free Taq DNA polymerase ideally suited for the sensitive PCR analysis of microbial target DNA even at very low concentrations. Find out the benefits.

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SelectNA™plus - Robotic Pathogen DNA Extraction System

SelectNA™plus is the ‘Selective extraction of microbial Nucleic Acids’ from mixtures including host and microbial cells providing a ‘plus’ benefit by walk-away automated processing of clinical samples. This highly enriched microbial DNA guarantees highest analytical performance in research and routine diagnosis.

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