Molzym Blog

Molzym Blog

Stay informed on topics covering pathogen enrichment and DNA isolation from clinical samples, automation, molecular diagnostics and Next-Generation Sequencing. We keep you informed on new developments, give practical tips and provide an inside view on Molzym.

Categories:

Pathogen DNA Isolation NGS Automation
DNA-Free Reagents Molecular Diagnostics Newsletter
 
Molzym Inside   
 

Latest blog posts - Click here for the list of our latest blog posts

 

Selection of blog posts:

SepsiTest™-UMD: Unbiased rDNA PCR Pathogen Diagnosis

Rapid pathogen detection is essential for timely patient treatment. In contrast to culture, molecular methods provide results within hours. Molzym’s highly sensitive approach combines a unique DNA extraction technique with 16S and 18S rRNA gene PCR and amplicon sequencing for the identification of bacterial and fungal infections. See how it works.

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Vol 4/2018 - New Solutions for 16S Metagenomic Sequencing

Are you using next generation sequencing and looking for reagents and methods for infection diagnosis by microbiome analysis? The new NGSeq 16S V3/V4 is a master mix for the Amplicon PCR as part of the library preparation for 16S metagenomic sequencing with Illumina® MiSeq system. Discover its benefits and learn about other helpful methods.

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EU-Funded Project on Invasive Fungal Disease Detection

Invasive fungal disease is a major cause of morbidity and mortality in immuno-compromised patients. In a FP7 project of the European Commission, Molzym partners with 5 institutions from 4 countries to develop and evaluate in multi-centre clincial studies fast DNA, enzymatic and protein-based assays.

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Overview of MolYsis™ Applications in Research

Remove your host DNA for increased sensitivity for detection of microbes in a great variety of specimens, e.g body fluids and tissues. Here, we provide a collection of applications of MolYsis™ sample pre-treatment in combination with various analytical methods, including NGS, PCR and Real-time PCR, DNA arrays and amplicon cloning.

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Automated Microbial DNA Enrichment in Clinical Routine

Micro-Dx™ combines automated pathogen enrichment and DNA extraction with broad-range PCR and sequencing ID of species. A multi-centre analysis of 409 routine samples of tissues, fluids and swabs indicated acceptable diagnostic performance in comparison to other molecular tests and culture. Additional pathogens could be identified by Micro-Dx™.

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DNA-Free Hot MolTaq 16S/18S: Low Load Microbial DNA Detection

One of the major challenges in molecular microbe detection are false-positive results due to DNA contaminations of amplification reagents. Molzym’s new proprietary Hot MolTaq 16S/18S is a high quality, DNA-free Taq DNA polymerase ideally suited for the sensitive PCR analysis of microbial target DNA even at very low concentrations. Find out the benefits.

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